QuickBooks Error 40001 occurs during Direct Deposit activation due to insufficient user permissions, outdated software, corrupted company files, or internet issues. To fix it, run QuickBooks as Administrator, update to the latest version, verify your payroll subscription, repair QuickBooks using the Control Panel, and check your internet connection. Additionally, use the QuickBooks Tool Hub to troubleshoot and fix common issues. Contact support if the error persists.

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